Moderna and @Merck today announced positive topline results from the Phase 3 INTerpath-001 trial evaluating adjuvant treatment with intismeran autogene, a novel investigational mRNA-based individualized neoantigen therapy jointly developed by Merck and Moderna, in combination
— Moderna (@moderna_tx) August 19, 2026
Next generation cancer immunotherapy
Moderna mRNA 4157
$mRNA4157
First Phase 3 mRNA cancer vaccine from Moderna that crushed melanoma recurrence with Keytruda.
LOADING
- 01 mRNA technology
- 02 Targeted immunity
- 03 Clinically advanced
Clinical briefing
The protocol that moved from theory to Phase 3
$mRNA4157 is the Solana memecoin named for Moderna mRNA-4157 — the individualized neoantigen therapy that just posted positive Phase 3 topline results in adjuvant melanoma.
Why the vial matters
Moderna and Merck reported positive topline results from INTerpath-001: adjuvant intismeran autogene plus pembrolizumab (Keytruda) in completely resected Stage IIB-IV melanoma. It is the first combination regimen to show a clinically meaningful improvement over Keytruda alone — the current standard of care.
For years the idea was science fiction: read a tumor’s genetic fingerprint, write an mRNA medicine for that patient, and train the immune system to hunt what surgery left behind. Phase 3 put a number on it. Recurrence got crushed.
This site is the Solana translation of that moment. Same name. Same symbol. Same story the world just watched land.
- Compound
- Intismeran autogene / mRNA-4157 / V940
- Partner
- Keytruda (pembrolizumab)
- Study
- Phase 3 INTerpath-001
- Chain
- Solana
mRNA technology
A writable strand. Tumor mutations in, personalized antigen cassette out. The platform that already shipped infectious-disease vaccines now writes oncology.
Targeted immunity
Not a blunt instrument. Neoantigens unique to the patient’s tumor, presented so T-cells learn the exact silhouette of what they are hunting.
Precision targeting
Adjuvant setting. After resection. The window where recurrence used to hide — now a Phase 3 readout against Keytruda alone.
Acquisition protocol
How to buy $mRNA4157
Four clinical steps. Phantom wallet, Solana, PumpSwap. No prescription required.
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01
Prepare a Solana wallet
Install Phantom and create a wallet. This is your sterile field — the only instrument that signs the swap.
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02
Load SOL
Bridge or buy SOL and send it to Phantom. Keep a small reserve for network fees so the dose can clear.
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03
Open PumpSwap
Connect the wallet on PumpSwap. Paste the $mRNA4157 contract from the specimen strip above.
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04
Swap and confirm
Select SOL to $mRNA4157, review the route, and confirm. Chart the fill on Dexscreener the moment it lands.
Live readout
Dexscreener chart
Solana market tape, embedded from Dexscreener. No extra widgets. No second chart.
Enrollment
Join the protocol
The Phase 3 story is public. The Solana ticker is $mRNA4157. Follow the feed, watch the chart, and step into the vial with the rest of the cohort.